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This Vaccine was developed by William Coley, a surgeon in 1893 at the New York Cancer Hospital. Coley discovered that when his vaccine caused a fever, the cancer shrank and number of immune cells increased dramatically. Usually, fevers are suppressed with medicinal drugs like acetaminophen, aspirin or ibuprofen. But studies have shown that suppressing a fever not only makes the infection worse but also spreads it. Coley recognized the beneficial effects of fever in cancer patients. He also discovered that when he stopped injecting the vaccine too early, the cancer started growing again. Thus, immune cells could be stimulated to fight the cancer for a limited time only. So, he used repeated injections to stimulate the immune system continuously. |
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